Dymista Nasal Spray contains azelastine hydrochloride, an antihistamine, and fluticasone propionate, a corticosteroid, used together to treat moderate to severe allergic rhinitis. This includes symptoms such as nasal congestion, runny nose, sneezing, and itching caused by seasonal allergies like hay fever or year-round triggers such as dust mites and pet dander.

Azelastine works by blocking the effects of histamine to relieve itching and sneezing, while fluticasone reduces inflammation in the nasal passages to ease congestion. The spray is applied directly into each nostril, usually twice daily, providing fast and long-lasting relief when used regularly as prescribed.