Fucidin H Cream combines hydrocortisone acetate, a mild corticosteroid that reduces inflammation, redness, and itching, with fusidic acid, an antibiotic effective against certain bacteria such as Staphylococcus aureus. It is used to treat inflamed skin conditions, including eczema or dermatitis, when they are infected or likely to become infected. Hydrocortisone soothes irritation and swelling, while fusidic acid works to eliminate the bacteria causing or worsening the condition.

The cream is applied thinly to the affected area, usually two to three times daily, for a short treatment period. It should be used exactly as prescribed to avoid overuse or resistance.